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Review
. 2005 May-Jun;10(3):031102.
doi: 10.1117/1.1922927.

Infrared analysis of bone in health and disease

Adele Boskey  1 , Richard Mendelsohn
Affiliations
Free article
Review

Infrared analysis of bone in health and disease

Adele Boskey et al. J Biomed Opt. 2005 May-Jun.
Free article

Abstract

Infrared spectroscopy, microspectroscopy, and microspectroscopic imaging have been used to probe the composition and physicochemical status of mineral and matrix of bone in normal and diseased tissues using a series of validated parameters that reflect quantitative and qualitative properties. In this review, emphasis is placed on changes in bone's composition and physiochemical status during osteoporosis and the impact of currently used therapeutics on these parameters, although the impact of infrared microscopy in other pathological states is briefly discussed.

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