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. 2005 Sep;11(9):1376-81.
doi: 10.3201/eid1109.041043.

Dengue virus type 3, Brazil, 2002

Rita Maria Ribeiro Nogueira  1 , Hermann Gonçalves Schatzmayr, Ana Maria Bispo de Filippis, Flávia Barreto dos Santos, Rivaldo Venâncio da Cunha, Janice Oliveira Coelho, Luiz José de Souza, Flávia Ramos Guimarães, Eliane Saraiva Machado de Araújo, Thatiane Santos De Simone, Meri Baran, Gualberto Teixeira Jr, Marize Pereira Miagostovich
Affiliations

Dengue virus type 3, Brazil, 2002

Rita Maria Ribeiro Nogueira et al. Emerg Infect Dis. 2005 Sep.

Abstract

During the summer of 2002, Rio de Janeiro had a large epidemic of dengue fever; 288,245 cases were reported. A subset of 1,831 dengue hemorrhagic fever cases occurred. In this study, performed in the first half of 2002, samples from 1,559 patients with suspected cases of dengue infection were analyzed. From this total, 1,497 were obtained from patients with nonfatal cases, and 62 were obtained from patients with fatal cases. By the use of different methods, 831 (53.3%) cases, including 40 fatal cases, were confirmed as dengue infection. When virus identification was successful, dengue virus type 3 (DENV-3) was obtained in 99% of cases. Neurologic involvement was shown in 1 patient with encephalitis, confirmed by the detection of DENV-3 RNA in the cerebrospinal fluid. This explosive epidemic of DENV-3 was the most severe dengue epidemic reported in Brazil since dengue viruses were introduced in 1986.

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References

    1. Rosen L. Comments on the epidemiology, pathogenesis and control of dengue. Med Trop (Mars). 1999;59:495–8. - PubMed
    1. Gubler DJ. Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century. Trends Microbiol. 2002;10:100–3. 10.1016/S0966-842X(01)02288-0 - DOI - PubMed
    1. Guzman MG, Kouri G. Dengue and dengue hemorrhagic fever in the Americas: lessons and challenges. J Clin Virol. 2003;27:1–13. 10.1016/S1386-6532(03)00010-6 - DOI - PubMed
    1. Nogueira RMR, Miagostovich MP, Schatzmayr HG. Dengue virus in Brazil. Dengue Bull. 2002;26:1–10.
    1. Centers for Disease Control and Prevention. Dengue 3 in Central America. Dengue surveillance summary. San Juan, Puerto Rico: The Centers; 1995. p. 1–3.

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