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. 2005 Sep;11(9):1464-6.
doi: 10.3201/eid1109.050182.

Beta-lactam resistance and Enterobacteriaceae, United States

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Beta-lactam resistance and Enterobacteriaceae, United States

Jean M Whichard et al. Emerg Infect Dis. 2005 Sep.

Abstract

Extended-spectrum cephalosporins (ESC) are an important drug class for treating severe Salmonella infections. We screened the human collection from the National Antimicrobial Resistance Monitoring System 2000 for ESC resistance mechanisms. Of non-Typhi Salmonella tested, 3.2% (44/1,378) contained blaCMY genes. Novel findings included blaCMY-positive Escherichia coli O157:H7 and a blaSHV-positive Salmonella isolate. CMY-positive isolates showed a ceftriaxone MIC > or =2 microg/mL.

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References

    1. Hohmann EL. Nontyphoidal salmonellosis. Clin Infect Dis. 2001;32:263–9. 10.1086/318457 - DOI - PubMed
    1. Centers for Disease Control and Prevention. PHLIS Salmonella 2000 annual summary. Division of Bacterial and Mycotic Diseases. 2001. [cited 2005 Jan 10]. Available at http://www.cdc.gov/ncidod/dbmd/phlisdata/salmonella.htm#2000
    1. Dunne EF, Fey PD, Kludt P, Reporter R, Mostashari F, Shillam P, et al. Emergence of domestically acquired ceftriaxone-resistant Salmonella infections associated with AmpC β-lactamase. JAMA. 2000;284:3151–6. 10.1001/jama.284.24.3151 - DOI - PubMed
    1. Carattoli A, Tosini F, Giles WP, Rupp ME, Hinrichs SH, Angulo FJ, et al. Characterization of plasmids carrying CMY-2 from expanded-spectrum cephalosporin-resistant Salmonella strains isolated in the United States between 1996 and 1998. Antimicrob Agents Chemother. 2002;46:1269–72. 10.1128/AAC.46.5.1269-1272.2002 - DOI - PMC - PubMed
    1. Miriagou V, Tzouvelekis LS, Rossiter S, Tzelepi E, Angulo FJ, Whichard JM. Imipenem resistance in a Salmonella clinical strain due to plasmid-mediated class A carbapenemase KPC-2. Antimicrob Agents Chemother. 2003;47:1297–300. 10.1128/AAC.47.4.1297-1300.2003 - DOI - PMC - PubMed

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