Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2005 Nov;2(11):e287.
doi: 10.1371/journal.pmed.0020287. Epub 2005 Oct 25.

The first randomised trial of male circumcision for preventing HIV: what were the ethical issues?

Peter Cleaton-Jones  1
Affiliations
Comment

The first randomised trial of male circumcision for preventing HIV: what were the ethical issues?

Peter Cleaton-Jones. PLoS Med. 2005 Nov.

Abstract

Cleaton-Jones, chair of the ethics committee that approved the trial of circumcision for preventing HIV, shares with us the discussions that the committee had ahead of granting approval.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The author has declared that no competing interests exist.

Comment in

  • A landmark paper in HIV research?
    [No authors listed] [No authors listed] PLoS Med. 2005 Nov;2(11):e293. doi: 10.1371/journal.pmed.0020293. Epub 2005 Oct 25. PLoS Med. 2005. PMID: 16231994 Free PMC article. No abstract available.
  • The money issue.
    Selemogo M. Selemogo M. PLoS Med. 2006 Jan;3(1):e73; author reply e67. doi: 10.1371/journal.pmed.0030073. Epub 2006 Jan 31. PLoS Med. 2006. PMID: 16435903 Free PMC article. No abstract available.

Comment on

References

    1. Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, et al. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 trial. PLoS Med. 2005;2:e298. doi: 10.1371/journal.pmed.0020298. - DOI - PMC - PubMed
    1. Beecher HK. Ethics and clinical research. New Engl J Med. 1966;274:1354–1360. - PubMed
    1. Medical Research Council of South Africa. Guidelines on ethics for medical research: General principles, revised ed. Tygerberg (South Africa): Medical Research Council of South Africa; 2002. Available: http://www.sahealthinfo.org/ethics/ethicsbook1.pdf. Accessed 30 September 2005.
    1. United States National Archives and Records Administration. Code of federal regulations, title 45—Public welfare: Part 46—Protection of human subjects. Bethesda: Department of Health and Human Services, General Administration, National Institutes of Health; 2001. Available: http://www.access.gpo.gov/nara/cfr/waisidx_01/45cfr46_01.html. Accessed 26 July 2005.
    1. Department of Health, Republic of South Africa. National HIV and syphilis antenatal sero-prevalence survey in South Africa 2004. 2004 Available: http://www.doh.gov.za/docs/reports/2004/hiv-syphilis.pdf. Accessed 28 September 2005.