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Comment
. 2005 Nov;2(11):e393.
doi: 10.1371/journal.pmed.0020393. Epub 2005 Oct 25.

Does male circumcision prevent HIV infection?

Affiliations
Comment

Does male circumcision prevent HIV infection?

Nandi Siegfried. PLoS Med. 2005 Nov.

Abstract

Siegfried discusses the first reported randomized controlled trial of whether circumcision protects against HIV, published in PLoS Medicine.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: NS is the lead author of a Cochrane systematic review of observational studies of this topic and has advocated for the need for randomised trials to assess the effects of male circumcision. She has no financial or other competing interests in male circumcision.

Comment in

  • A landmark paper in HIV research?
    [No authors listed] [No authors listed] PLoS Med. 2005 Nov;2(11):e293. doi: 10.1371/journal.pmed.0020293. Epub 2005 Oct 25. PLoS Med. 2005. PMID: 16231994 Free PMC article. No abstract available.

Comment on

References

    1. Moses S, Plummer FA, Bradley JE, Ndiya-Achola JO, Nagelkerke NJD, et al. The association between lack of male circumcision and risk for HIV infection: A review of the epidemiological data. Sex Transm Dis. 1994;21:201–210. - PubMed
    1. DeVincenzi ID, Mertens T. Male circumcision: A role in HIV prevention? AIDS. 1994;8:153–160. - PubMed
    1. Moses S, Bailey RC, Donald AR. Male circumcision: Assessment of health benefits and risks. Sex Transm Dis. 1998;74:368–373. - PMC - PubMed
    1. Howe RV. Circumcision and HIV infection: Review of the literature and meta-analysis. Int J STD AIDS. 1999;10:8–16. - PubMed
    1. Weiss HA, Quigley MA, Hayes R. Male circumcision and risk of HIV infection in sub-Saharan Africa: A systematic review and meta-analysis. AIDS. 2000;14:2361–2370. - PubMed