doi: 10.1263/jbb.100.127.
Transition of mechanical property of porous alginate scaffold with cells during culture period
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- PMID: 16233864
- DOI: 10.1263/jbb.100.127
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Transition of mechanical property of porous alginate scaffold with cells during culture period
J Biosci Bioeng.
2005 Jul.
Abstract
The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.
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