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. 2005 Jul;100(1):127-9.
doi: 10.1263/jbb.100.127.

Transition of mechanical property of porous alginate scaffold with cells during culture period

Shinji Sakai  1 , Hiroki Masuhara, Yusuke Yamada, Tsutomu Ono, Hiroyuki Ijima, Koei Kawakami
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Transition of mechanical property of porous alginate scaffold with cells during culture period

Shinji Sakai et al. J Biosci Bioeng. 2005 Jul.

Abstract

The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.

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