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. 2006 Feb;60(2):228-35.
doi: 10.1038/sj.ejcn.1602306.

Epidemiology of anemia among 4- to 17-month-old children living in south central Nepal

E H Siegel  1 , R J Stoltzfus, S K Khatry, S C Leclerq, J Katz, J M Tielsch
Affiliations

Epidemiology of anemia among 4- to 17-month-old children living in south central Nepal

E H Siegel et al. Eur J Clin Nutr. 2006 Feb.

Abstract

Objective: To describe the distribution of hemoglobin and prevalence of anemia in Nepali children living in the Terai region by potential risk factors for deficiency.

Design: This was a cross-sectional, community-based study of baseline characteristics of children enrolled in a randomized, placebo-controlled clinical trial between January and March 2002. Participants were weighed and measured and had their blood drawn. Their mothers contributed demographic, morbidity, and feeding data.

Subjects: There were 569 4- to 17-month-old children. Statistical models were based on 490 children.

Results: Anemia was prevalent: 58% of the children had a hemoglobin <105 g/l. Iron-deficiency anemia (anemia with erythrocyte protoporphyrin (EP) > or =90 micromol/mol heme) was present in 43% of the children. Severe anemia was rare: less than 2% of the children had a hemoglobin <70 g/l. The mean (s.d.) hemoglobin concentration was 101 (12.5) g/l. Stunting and wasting were prevalent: 30.8% were stunted (length-for-age Z-score <-2) and 18.1% were wasted (weight-for-length Z-score <-2). Bivariate analyses revealed that age, caste, socioeconomic status, dietary diversity, stunting, and underweight were associated with hemoglobin concentration and/or anemia. In multivariate models with and without EP, age and caste were found to be strong predictors of both hemoglobin concentration and anemia.

Conclusions: Anemia and iron deficiency increased strongly with age and low-caste status among the study children. The data reveal the importance of targeting interventions to children in the first year of life before they become anemic and iron deficient.

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Figures

Figure 1
Figure 1
Reported consumption of selected foods in the past 7 days, by age
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References

    1. Beard J. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr. 2001;131:568S–580S. - PubMed
    1. Bentley ME, Griffiths PL. The burden of anemia among women in India. Eur J Clin Nutr. 2003;57(1):52–60. - PubMed
    1. Brown KH, Peerson JM, Lopez de Romana G, de Kanashiro HC, Black RE. Validity and epidemiology of reported poor appetite among Peruvian infants from a low-income, periurban community. Am J Clin Nutr. 1995;61(1):26–32. - PubMed
    1. Christian P, Khatry SK, Katz J, Pradhan EK, LeClerq SC, Shrestha SR, Adhikari RK, Sommer A, West KP., Jr Supplementation with micronutrients in addition to iron and folic acid does not further improve the hematologic status of pregnant women in rural Nepal. J Nutr. 2003;133(11):3492–8. - PubMed
    1. Chronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika. 1951;16:297–334.

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