Kidney dysfunction in the recipients of liver transplants
- PMID: 16237714
- DOI: 10.1002/lt.20618
Kidney dysfunction in the recipients of liver transplants
Abstract
1. Pretransplant kidney function is an important predictor of posttransplant kidney function. 2. Chronic kidney disease is present in 20% of liver transplant recipients by 5 years. 3. Kidney function is impacted by pretransplant management of the consequences of the hepatorenal syndrome. 4. The use of calcineurin inhibitor (CNI)-based immunosuppression is an important factor in the development of chronic kidney disease, and the use of mycophenolic acid- or sirolimus-based immunosuppression with reduced-dose CNI may be of benefit.
Similar articles
-
A randomized controlled trial of late conversion from calcineurin inhibitor (CNI)-based to sirolimus-based immunosuppression in liver transplant recipients with impaired renal function.Liver Transpl. 2007 Dec;13(12):1694-702. doi: 10.1002/lt.21314. Liver Transpl. 2007. PMID: 18044728 Clinical Trial.
-
Sirolimus in cardiac transplantation: use as a primary immunosuppressant in calcineurin inhibitor-induced nephrotoxicity.J Heart Lung Transplant. 2005 Dec;24(12):2129-36. doi: 10.1016/j.healun.2005.08.015. J Heart Lung Transplant. 2005. PMID: 16364861 Clinical Trial.
-
Replacement of calcineurin-inhibitors with sirolimus as primary immunosuppression in stable cardiac transplant recipients.Transplantation. 2007 Aug 27;84(4):467-74. doi: 10.1097/01.tp.0000276959.56959.69. Transplantation. 2007. PMID: 17713429 Clinical Trial.
-
Calcineurin nephrotoxicity.Adv Chronic Kidney Dis. 2006 Jan;13(1):47-55. doi: 10.1053/j.ackd.2005.11.001. Adv Chronic Kidney Dis. 2006. PMID: 16412970 Review.
-
Chronic allograft dysfunction: can we use mammalian target of rapamycin inhibitors to replace calcineurin inhibitors to preserve graft function?Curr Opin Organ Transplant. 2008 Dec;13(6):614-21. doi: 10.1097/MOT.0b013e3283193bad. Curr Opin Organ Transplant. 2008. PMID: 19060552 Review.
Cited by
-
Sustained renal response to mycophenolate mofetil and CNI taper promotes survival in liver transplant patients with CNI-related renal dysfunction.Dig Dis Sci. 2011 Jan;56(1):244-51. doi: 10.1007/s10620-010-1386-z. Epub 2010 Sep 8. Dig Dis Sci. 2011. PMID: 20824504
-
Evidence for the immunosuppressive potential of calcineurin inhibitor-sparing regimens in liver transplant recipients with impaired renal function.J Transplant. 2011;2011:483728. doi: 10.1155/2011/483728. Epub 2011 Jul 6. J Transplant. 2011. PMID: 21785695 Free PMC article.
-
Acute kidney injury and post-reperfusion syndrome in liver transplantation.World J Gastroenterol. 2016 Nov 14;22(42):9314-9323. doi: 10.3748/wjg.v22.i42.9314. World J Gastroenterol. 2016. PMID: 27895419 Free PMC article. Review.
-
Sequential Cohort Analysis After Liver Transplantation Shows de Novo Extended Release Tacrolimus Is Safe, Efficacious, and Minimizes Renal Dysfunction.Transplant Direct. 2020 Jan 17;6(2):e528. doi: 10.1097/TXD.0000000000000970. eCollection 2020 Feb. Transplant Direct. 2020. PMID: 32095514 Free PMC article.
-
Pre-transplant kidney function predicts chronic kidney disease after liver transplant: meta-analysis of observational studies.Dig Dis Sci. 2011 May;56(5):1282-9. doi: 10.1007/s10620-010-1529-2. Epub 2011 Jan 8. Dig Dis Sci. 2011. PMID: 21221799
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical