Review
doi: 10.1016/j.chembiol.2005.10.002.
The stereochemistry of ketoreduction
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- PMID: 16242648
- DOI: 10.1016/j.chembiol.2005.10.002
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Review
The stereochemistry of ketoreduction
Chem Biol.
2005 Oct.
Abstract
In this issue of Chemistry & Biology, Leadlay and coworkers report overproduction of a number of ketoreductase domains from modular polyketide synthases. These discrete enzymes allow the stereochemistry of polyketide ketoreduction to be studied in isolation.
Comment on
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Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases.Chem Biol. 2005 Oct;12(10):1145-53. doi: 10.1016/j.chembiol.2005.08.017. Chem Biol. 2005. PMID: 16242657
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