doi: 10.1016/j.micinf.2005.07.015.
Epub 2005 Sep 15.
Vaccines based on Nef and on Nef/DeltaV2 Env
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- PMID: 16243564
- DOI: 10.1016/j.micinf.2005.07.015
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Vaccines based on Nef and on Nef/DeltaV2 Env
Microbes Infect.
2005 Nov.
Free article
Abstract
Modified vaccinia virus Ankara (MVA) is a potent vaccine vector, which proved its safety, immunogenity and efficacy in preclinical and clinical studies. The rational for the development of a vaccine against HIV based on the regulatory protein Nef delivered by MVA combined with a V2-deleted Env protein is discussed.
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