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. 2005 Nov;7(14):1400-4.
doi: 10.1016/j.micinf.2005.07.015. Epub 2005 Sep 15.

Vaccines based on Nef and on Nef/DeltaV2 Env

Volker Erfle  1 , Frank D Goebel, Carlos A Guzman, Roger Le Grand
Affiliations
Free article

Vaccines based on Nef and on Nef/DeltaV2 Env

Volker Erfle et al. Microbes Infect. 2005 Nov.
Free article

Abstract

Modified vaccinia virus Ankara (MVA) is a potent vaccine vector, which proved its safety, immunogenity and efficacy in preclinical and clinical studies. The rational for the development of a vaccine against HIV based on the regulatory protein Nef delivered by MVA combined with a V2-deleted Env protein is discussed.

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