E Pluribus Unum: 3' end formation of polyadenylated mRNAs, histone mRNAs, and U snRNAs
- PMID: 16246719
- DOI: 10.1016/j.molcel.2005.10.009
E Pluribus Unum: 3' end formation of polyadenylated mRNAs, histone mRNAs, and U snRNAs
Abstract
The 3' ends of almost all eukaryotic RNAs are generated by nucleolytic cleavage. Remarkably, three groups now demonstrate that similar or identical endonucleases of the metallo-beta-lactamase family generate the 3' ends of polyadenylated mRNAs, nonpolyadenylated histone mRNAs, and U snRNAs.
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