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. 2005 Jul;19(14):640-2, 645.

[Study on the expression of HSP70 and HSP90beta in nasopharyngeal carcinoma and the clinical significance]

[Article in Chinese]
Tao Liu  1 , Chuanyu Liang, Ling Tian, Yuquan Wei, Jumei Zhao
Affiliations
  • PMID: 16248461

[Study on the expression of HSP70 and HSP90beta in nasopharyngeal carcinoma and the clinical significance]

[Article in Chinese]
Tao Liu et al. Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2005 Jul.

Abstract

Objective: To study the expression of HSP70 and HSP90beta and its clinical significance in human nasopharyngeal carcinoma.

Method: Immunohistochemical method SP was used to detect the expression of HSP70 and HSP90beta in 50 cases and its clinical significance were studied.

Result: The positive rate of HSP70 and HSP90beta were 72% and 56% respectively. Analysis of patients, survival demonstrated that the prognosis of NPC with HSP70 (-) and HSP90beta (-) expression were significantly better than the others.

Conclusion: The overexpression of HSP70 and HSP90beta were probably concerned with the occurrence, development and prognosis of nasopharyngeal carcinoma.

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