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Comment
. 2005 Nov;77(5):892-4; author reply 894-5.
doi: 10.1086/497082.

Narrowing the candidate region for congenital diaphragmatic hernia in chromosome 15q26: contradictory results

L Castiglia, M Fichera, C Romano, O Galesi, L Grillo, M Sturnio, P Failla
Comment

Narrowing the candidate region for congenital diaphragmatic hernia in chromosome 15q26: contradictory results

L Castiglia et al. Am J Hum Genet. 2005 Nov.
No abstract available

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Figures

Figure  1
Figure  1
Graphical representation of 15q deletions in patients with and without CDH. The most significant BAC clones analyzed are shown on the left. Solid boxes represent deleted regions, hatched boxes indicate the uncertainty of the breakpoints, and open boxes reveal the normal chromosomal regions. The green rectangle includes the narrowed candidate CDH region, taking into account only cases with CDH, whereas the red rectangle indicates the critical region resulting when the ring cases are omitted from the analysis. Patient 1, our case; patient 2, Tönnies et al. ; patient 3, Rogan et al. (patient K); patients 4–11 and 13, Klaassens et al. (cases 9, 7, 6, 4, 1, 2, 3, 5, and 8, respectively); patient 12, Tümer et al. (case 1).
See this image and copyright information in PMC

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References

Web Resources

    1. NCBI Map Viewer, http://www.ncbi.nlm.nih.gov/mapview/
    1. Online Mendelian Inheritance in Man (OMIM), http://www.ncbi.nlm.nih.gov/Omim/

References

    1. Allan DW, Greer JJ (1998) Polysialylated NCAM expression during motor axon outgrowth and myogenesis in the fetal rat. J Comp Neurol 391:275-29210.1002/(SICI)1096-9861(19980216)391:3<275::AID-CNE1>3.0.CO;2-Z - DOI - PubMed
    1. Angata K, Nakayama J, Fredette B, Chong K, Ranscht B, Fukuda M (1997) Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule: tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST. J Biol Chem 272:7182–719010.1074/jbc.272.11.7182 - DOI - PubMed
    1. Biggio JR, Descartes MD, Carroll AJ, Holt RL (2004) Congenital diaphragmatic hernia: is 15q26.1–26.2 a candidate locus? Am J Med Genet A 126:183–18510.1002/ajmg.a.20464 - DOI - PubMed
    1. Harrison MR, Adzick NS, Estes JM, Howell LJ (1994) A prospective study of the outcome for fetuses with diaphragmatic hernia. JAMA 271:382–38410.1001/jama.271.5.382 - DOI - PubMed
    1. Klaassens M, van Dooren M, Eussen HJ, Douben H, den Dekker AT, Lee C, Donahoe PK, Galjaard RJ, Goemaere N, de Krijger RR, Wouters C, Wauters J, Oostra BA, Tibboel D, de Klein A (2005) Congenital diaphragmatic hernia and chromosome 15q26: determination of a candidate region by use of fluorescence in situ hybridization and array-based comparative genomic hybridization. Am J Hum Genet 76:877–882 - PMC - PubMed

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