Mechanism underlying the effect of myelopeptides on lymphocyte proliferation in vitro
- PMID: 16254625
- DOI: 10.1007/s10517-005-0415-y
Mechanism underlying the effect of myelopeptides on lymphocyte proliferation in vitro
Abstract
We studied the role of monocytes in the effect of myelopid and myelopeptides MP-1, MP-3, MP-5, and MP-6 on functional activity of peripheral blood lymphocytes in the reaction of blast transformation. Myelopeptides MP-1, MP-3, and MP-6 suppressed blast transformation of lymphocytes. The effect depended on the presence of monocytes in a cell culture.
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