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. 2005 Nov;7(14):1414-23.
doi: 10.1016/j.micinf.2005.07.017. Epub 2005 Sep 29.

The rationale behind a vaccine based on multiple HIV antigens

E Rollman  1 , A Bråve, A Boberg, L Gudmundsdotter, G Engström, M Isaguliants, K Ljungberg, B Lundgren, P Blomberg, J Hinkula, B Hejdeman, E Sandström, M Liu, B Wahren
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Free article

The rationale behind a vaccine based on multiple HIV antigens

E Rollman et al. Microbes Infect. 2005 Nov.
Free article

Abstract

The viral diversity of HIV-1 is likely to require a vaccine strategy that induces broad cellular and humoral anti-HIV-1 immunity. Our strategy is based on multiple HIV-1 DNA immunogens together with adjuvant recombinant granulocyte-macrophage stimulating factor. This article describes pre-clinical and clinical work preceding the initiation of clinical HIV-1 phase I/II trials.

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