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. 2005 Aug;58(8):535-8.
doi: 10.1038/ja.2005.74.

Structure elucidation of Sch 725674 from Aspergillus sp

Shu-Wei Yang  1 , Tze-Ming Chan, Joseph Terracciano, David Loebenberg, Mahesh Patel, Min Chu
Affiliations

Structure elucidation of Sch 725674 from Aspergillus sp

Shu-Wei Yang et al. J Antibiot (Tokyo). 2005 Aug.

Abstract

A new macrolide Sch725674 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was accomplished based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 8 and 32 microg/ml, respectively.

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