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. 2005 Oct;220(Pt 1):70-5.
doi: 10.1111/j.1365-2818.2005.01510.x.

In vivo assessment of emphysema in mice by high resolution X-ray microtomography

A A Postnov  1 , K Meurrens, H Weiler, D Van Dyck, H Xu, P Terpstra, N M De Clerck
Affiliations

In vivo assessment of emphysema in mice by high resolution X-ray microtomography

A A Postnov et al. J Microsc. 2005 Oct.

Abstract

High resolution X-ray microtomography (micro-CT) was used for the detection of emphysema in live mice. Emphysema was induced in C57BL/6 J mice by intratracheal instillation of different amounts of porcine pancreatic elastase. This emphysema could be clearly detected by micro-CT seven weeks post-treatment: analysis of the whole data set of virtual cross-sections showed the presence of a dose-dependent level of emphysema.

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