An E-MAP of the ER
- PMID: 16269327
- DOI: 10.1016/j.cell.2005.10.016
An E-MAP of the ER
Abstract
Genome-wide phenotype mapping has the potential to provide insights into gene function on an unprecedented scale. In this issue of Cell, Schuldiner et al.(2005) show that saturation epistasis analysis of genes implicated in the early secretory pathway in yeast provides a new strategy for uncovering functional relationships using high-throughput genomic data.
Comment on
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Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.Cell. 2005 Nov 4;123(3):507-19. doi: 10.1016/j.cell.2005.08.031. Cell. 2005. PMID: 16269340
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