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Review
. 2005 Nov 4;123(3):375-82.
doi: 10.1016/j.cell.2005.10.015.

Membrane hemifusion: crossing a chasm in two leaps

Leonid V Chernomordik  1 , Michael M Kozlov
Affiliations
Free article
Review

Membrane hemifusion: crossing a chasm in two leaps

Leonid V Chernomordik et al. Cell. .
Free article

Abstract

During membrane fusion, the outer leaflets of the two membranes merge first, whereas the distal membrane leaflets remain separate until the opening of a fusion pore. This intermediate stage, called hemifusion, is a critical event shared by exocytosis, protein trafficking, and viral entry.

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