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. 2005 Nov 8;15(21):R880-2.
doi: 10.1016/j.cub.2005.10.022.

Centrosome maturation: Aurora lights the way to the poles

Amy L Brittle  1 , Hiroyuki Ohkura
Affiliations
Free article

Centrosome maturation: Aurora lights the way to the poles

Amy L Brittle et al. Curr Biol. .
Free article

Abstract

The centrosome is the main microtubule organising centre in the cell. During mitosis, centrosomes dramatically increase microtubule nucleating activity, enabling them to form a mitotic spindle. Recent studies show that Aurora A kinase promotes microtubule assembly from centrosomes through the phosphorylation of the conserved centrosomal protein TACC.

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