Paroxetine (Paxil) and congenital malformations
- PMID: 16272192
- PMCID: PMC1283495
- DOI: 10.1503/cmaj.051421
Paroxetine (Paxil) and congenital malformations
References
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- Einarson TR, Einarson A. Newer antidepressants in pregnancy and rates of major malformations: a meta-analysis of prospective comparative studies. Pharmacoepidemiol Drug Saf 2005;Mar 1 [Epub ahead of print]. DOI:10.1002/pds.1084 - PubMed
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- GlaxoSmithKline study EPIP083. GSK medicine: bupropion and paroxetine. Epidemiology study: preliminary report on bupropion in pregnancy and the occurrence of cardiovascular and major congenital malformation. Available: http ://ctr.gsk.co.uk/summary/paroxetine/epip083.pdf (accessed 2005 Oct 26); also archived at www.cmaj.ca/cgi/content/full/173/11/1320/DC1 as an appendix.
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- Dillon AJ, for GlaxoSmithKline Inc., encorsed by Health Canada. New safety information regarding paroxetine. Findings suggest increased risk over other antidepressants, of congenital malformations, following first trimester exposure to paroxetine [Dear Health Care Professional letter]. Available: www.hc-sc.gc.ca/dhp-mps/medeff/advisories-avis/prof/paxil_3_hpc-cps_e.html (accessed 2005 Oct 26).
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- Hallberg P, Sjoblom V. The use of selective serotonin reuptake inhibitors during pregnancy and breast-feeding: a review and clinical aspects [review]. J Clin Psychopharmacol 2005;25:59-73. - PubMed
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