Recruitment maneuvers and positive end-expiratory pressure/tidal ventilation titration in acute lung injury/acute respiratory distress syndrome: translating experimental results to clinical practice
- PMID: 16277726
- PMCID: PMC1297626
- DOI: 10.1186/cc3800
Recruitment maneuvers and positive end-expiratory pressure/tidal ventilation titration in acute lung injury/acute respiratory distress syndrome: translating experimental results to clinical practice
Abstract
Recruitment maneuvers and positive end-expiratory pressure (PEEP)/tidal ventilation titration in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) are the cornerstone of mechanical ventilatory support. The net result of these possible adjustments in ventilatory parameters is the interaction of the pressure applied in the respiratory system (airway pressure/end expiratory pressure) counterbalanced by chest wall configuration/abdominal pressure along the mechanical ventilatory support duration. Refinements in the ventilatory adjustments in ALI/ARDS are necessary for minimizing the biotrauma in this still life-threatening clinical problem.
Figures
References
-
- Henzler D, Pelosi P, Dembinski R, Ullmann A, Mahnken AH, Rossaint R, Kuhlen R. Respiratory compliance but not gas exchange correlates with changes in lung aeration after a recruitment maneuver: an experimental study in pigs with saline lavage lung injury. Critical Care. 2005;9:R471–R482. doi: 10.1186/cc3772. - DOI - PMC - PubMed
-
- Barbas CSV, Matos GFJ, Pincelli MP, Borges ER, Antunes T, Barros JM, Okamoto V, Borges JB, Amato MBP, Carvalho CRR. Mechanical ventilation in acute respiratory failure: recruitment and high positive end-expiratory pressure are necessary. Curr Opin Crit Care. 2005;11:18–28. doi: 10.1097/00075198-200502000-00004. - DOI - PubMed
-
- Amato MB, Barbas CS, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi-Filho G, Kairalla RA, Deheinzelin D, Munoz C, Oliveira R, Takagaki TY, Carvalho CR. Effect of prospective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med. 1998;338:347–354. doi: 10.1056/NEJM199802053380602. - DOI - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
