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Case Reports
. 2005;9(6):R725-8.
doi: 10.1186/cc3884. Epub 2005 Oct 27.

Prolonged refractory status epilepticus following acute traumatic brain injury: a case report of excellent neurological recovery

Affiliations
Case Reports

Prolonged refractory status epilepticus following acute traumatic brain injury: a case report of excellent neurological recovery

Adam D Peets et al. Crit Care. 2005.

Abstract

Introduction: Refractory status epilepticus (RSE) secondary to traumatic brain injury (TBI) may be under-recognized and is associated with significant morbidity and mortality.

Methods: This case report describes a 20 year old previously healthy woman who suffered a severe TBI as a result of a motor vehicle collision and subsequently developed RSE. Pharmacological coma, physiological support and continuous electroencephalography (cEEG) were undertaken.

Results: Following 25 days of pharmacological coma, electrographic and clinical seizures subsided and the patient has made an excellent cognitive recovery.

Conclusion: With early identification, aggressive physiological support, appropriate monitoring, including cEEG, and an adequate length of treatment, young trauma patients with no previous seizure history and limited structural damage to the brain can have excellent neurological recovery from prolonged RSE.

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References

    1. Mirski MA, Williams MA, Hanley DF. Prolonged pentobarbital and phenobarbital coma for refractory generalized status epilepticus. Crit Care Med. 1995;23:400–404. doi: 10.1097/00003246-199502000-00028. - DOI - PubMed
    1. Skaff PT, Labiner DM. Status epilepticus due to human parvovirus B19 encephalitis in an immunocompetent adult. Neurology. 2001;57:1336–1337. - PubMed
    1. Tanganelli P, Regesta G. Refractory tonic generalized status epilepticus. Report of a case of exceptionally prolonged duration. Eur Neurol. 1991;31:413–418. - PubMed
    1. Nishie M, Ogawa M, Kurahashi K. Epstein-Barr virus-associated encephalitis presenting as refractory status epilepticus that persisted for nearly 2 months with excellent recovery. Rinsho Shinkeigaku. 2003;43:422–426. - PubMed
    1. Lowenstein DH, Bleck T, MacDonald RL. It's time to revise the definition of status epilepticus. Epilepsia. 1999;40:120–122. doi: 10.1111/j.1528-1157.1999.tb02000.x. - DOI - PubMed

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