Oscillating probe aspiration thrombectomy: comparative in vitro evaluation of two concepts

Abstract

Aspiration thrombectomy supported by an oscillating metal probe within the catheter allows continuous aspiration of large thrombi without catheter obstruction. Thrombus aspiration assisted by an ultrasound-driven probe (frequency 26 kHz) and by an electric motor-driven probe (frequency 40 Hz) was compared in two different in vitro models: aspiration of large clots from a Petri dish and recanalization of thrombotic occlusions in a flow model. Comparable results were found for a 1 mm ultrasound-driven probe and a 0.5 mm motor-driven probe. The motor-driven device, however, seems to be more appealing for in vivo application because of its simplicity, probe flexibility, absence of thermal effects, and low cost.