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Randomized Controlled Trial
. 2005 Nov;24(11):1021-3.
doi: 10.1097/01.inf.0000183938.33484.bd.

Safety and immunogenicity of palivizumab (Synagis) administered for two seasons

Donald Null Jr  1 , Bernard Pollara, Penelope H Dennehy, Jean Steichen, Pablo J Sánchez, Laurence B Givner, David Carlin, Bernard Landry, Franklin H Top Jr, Edward Connor
Affiliations
Randomized Controlled Trial

Safety and immunogenicity of palivizumab (Synagis) administered for two seasons

Donald Null Jr et al. Pediatr Infect Dis J. 2005 Nov.

Abstract

To evaluate the safety and immunogenicity of palivizumab, 55 children who received palivizumab in the IMpact-RSV trial received 5 monthly doses of 15 mg/kg palivizumab (Synagis) during the subsequent year. The single child with an antipalivizumab titer of >1/40 had no associated serious adverse events and had expected serum palivizumab trough concentrations. Second year palivizumab prophylaxis was safe and well-tolerated.

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