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. 2005 Dec 15;40(5):600-8.
doi: 10.1097/01.qai.0000171726.17436.82.

Acceptability of exclusive breast-feeding with early cessation to prevent HIV transmission through breast milk, ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d'Ivoire

Renaud Becquet  1 , Didier K Ekouevi, Ida Viho, Charlotte Sakarovitch, Hassan Toure, Katia Castetbon, Nacoumba Coulibaly, Marguerite Timite-Konan, Laurence Bequet, François Dabis, Valériane Leroy
Affiliations

Acceptability of exclusive breast-feeding with early cessation to prevent HIV transmission through breast milk, ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d'Ivoire

Renaud Becquet et al. J Acquir Immune Defic Syndr. .

Abstract

Objective: We assessed the uptake of a nutritional intervention promoting exclusive breast-feeding with early cessation between 3 and 4 months of age to reduce postnatal transmission of HIV in Abidjan, Côte d'Ivoire.

Design: Between March 2001 and March 2003, HIV-infected pregnant women who had received perinatal antiretroviral prophylaxis were systematically offered prenatally 2 infant feeding interventions: artificial feeding or exclusive breast-feeding during 3 months and then early cessation of breast-feeding. Mother-infant pairs were closely followed for a period of 2 years, with continuous nutritional counseling and detailed collection of feeding practices.

Results: Among the 557 mothers enrolled, 262 (47%) initiated breast-feeding. Of these women, the probability of practicing exclusive breast-feeding from birth was 18% and 10% at 1 and 3 months of age, respectively. Complete cessation of breast-feeding was obtained in 45% and 63% by 4 and 6 months of age, respectively. Environmental factors such as living with a partner's family were associated with failure to initiate early cessation of breast-feeding.

Conclusions: Acceptability of exclusive breast-feeding was low in this urban population. Shortening the duration of breast-feeding seemed to be feasible, however. Further investigations are ongoing to evaluate the safety and effectiveness of this intervention in reducing breast milk HIV transmission.

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Conflict of interest statement

Conflict of interest

None of the authors had any conflict of interest to declare.

Figures

Figure 1
Figure 1
Cohort profile according to the infant feeding options. ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d’Ivoire
Figure 2
Figure 2
Infant feeding practices at ages M1, M3, M4, M6 and M9 in the breastfeeding group. ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d’Ivoire (N=262)
Figure 3
Figure 3
Kaplan-Meier probability of being exclusively breastfed from birth. ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d’Ivoire (N=262)
Figure 4
Figure 4
Kaplan-Meier probability of having initiated weaning and completely ceased breastfeeding. ANRS 1201/1202 Ditrame Plus, Abidjan, Côte d’Ivoire (N=262)
See this image and copyright information in PMC

References

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