Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2005 Nov;2(11):e399.
doi: 10.1371/journal.pmed.0020399. Epub 2005 Nov 29.

Restoring retinal function in a mouse model of hereditary blindness

Tony Moore  1
Affiliations
Comment

Restoring retinal function in a mouse model of hereditary blindness

Tony Moore. PLoS Med. 2005 Nov.

Abstract

Moore discusses a new study showing rescue of photoreceptor function using gene and drug therapies in a mouse model of Leber congenital amaurosis.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The author declares that no competing interests exist.

Figures

Figure 1
Figure 1. The Visual Cycle
(Illustration: Giovanni Maki, adapted from [4])
See this image and copyright information in PMC

Comment on

Similar articles

See all similar articles

Cited by

References

    1. Rahi JS, Cable N. Severe visual impairment and blindness in children in the UK. Lancet. 2003;362:1359–1365. - PubMed
    1. Batten ML, Imanishi Y, Tu DC, Doan T, Zhu L, et al. Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis. PLoS Med. 2005;2:e333. doi: 10.1371/journal.pmed.0020333. - DOI - PMC - PubMed
    1. Acland GM, Aguirre GD, Ray J, Zhang Q, Aleman TS, et al. Gene therapy restores vision in a canine model of childhood blindness. Nat Genet. 2001;28:92–95. - PubMed
    1. Sparrow JR. Therapy for macular degeneration: Insights from acne. Proc Natl Acad Sci U S A. 2003;100:4353–4354. - PMC - PubMed