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. 1975 Jan;14(1):40-2.

Adenosine 3',5'-monophosphate increases the outflow of aqueous humor from the rabbit eye

  • PMID: 162898

Adenosine 3',5'-monophosphate increases the outflow of aqueous humor from the rabbit eye

A H Neufeld et al. Invest Ophthalmol. 1975 Jan.

Abstract

Direct administration of cyclic-AMP into the anterior chamber increases the outflow facility of the eye for aqueous humor. This is consistent with the hypothesis that catecholamines lower the intraocular pressure of the rabbit eye, at least in part, by a cyclic-AMP-mediated mechanism. This mechanism is active in the outflow channels and increases the rate at which aqueous humor leaves the anterior chamber.

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