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. 2005 Nov;51(4):e225-8.
doi: 10.1016/j.jinf.2005.02.005.

Voriconazole-resistant disseminated Paecilomyces variotii infection in a neutropenic patient with leukaemia on voriconazole prophylaxis

Georgios Chamilos  1 , Dimitrios P Kontoyiannis
Affiliations

Voriconazole-resistant disseminated Paecilomyces variotii infection in a neutropenic patient with leukaemia on voriconazole prophylaxis

Georgios Chamilos et al. J Infect. 2005 Nov.

Abstract

Paecilomyces variotii, an emerging hyalohyphomycetes, has been reported to be susceptible in vitro to voriconazole. We describe a case of disseminated P. variotii infection in a neutropenic child with relapsed leukaemia who was on voriconazole prophylaxis. The P. variotii isolate was resistant to voriconazole in vitro. The patient responded to liposomal amphotericin B.

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