Review
doi: 10.2174/138955705774575264.
Are vanadium compounds drugable? Structures and effects of antidiabetic vanadium compounds: a critical review
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- PMID: 16307529
- DOI: 10.2174/138955705774575264
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Review
Are vanadium compounds drugable? Structures and effects of antidiabetic vanadium compounds: a critical review
Mini Rev Med Chem.
2005 Nov.
Abstract
Vanadate can be bioequivalent to phosphate and replace it in cellular metabolism. The detection of insulin-like activity has spurred interest in the development of oral anti-diabetic drugs containing vanadium. We collected and evaluated a vast toxicity data set and discussed molecular aspects related to insulin-mimetic effects of vanadium complexes.
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