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Case Reports
. 2005 Dec;13(6):471-3.
doi: 10.1080/09273940590951089.

Epstein-Barr Virus DNA quantification: an adjunctive diagnostic marker for AIDS-associated lymphoma

Shu Fen Ho  1 , Colin Fink, Philip I Murray
Affiliations
Case Reports

Epstein-Barr Virus DNA quantification: an adjunctive diagnostic marker for AIDS-associated lymphoma

Shu Fen Ho et al. Ocul Immunol Inflamm. 2005 Dec.

Abstract

We report an HIV-positive patient who developed a unilateral retinitis and subsequent intracranial lesions. The finding of Epstein Barr virus (EBV) DNA at a > 1-log greater concentration in the vitreous compared to blood raised the possibility of a primary CNS non-Hodgkin's lymphoma, which was subsequently confirmed on brain biopsy. EBV DNA quantification acted as a diagnostic marker that led to a change in the management of our patient.

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