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. 1975 Jan;54(1):269-70.
doi: 10.1093/jnci/54.1.269.

B-cell origin of hamster lymphoid tumors induced by simian virus 40

J E Coe, I Green

B-cell origin of hamster lymphoid tumors induced by simian virus 40

J E Coe et al. J Natl Cancer Inst. 1975 Jan.

Abstract

Two lymphoid neoplasms induced by simian virus 40 (SV40) in Syrian hamsters were analyzed for lymphocyte characteristics. The hymphocytes from both tumors contained membrane-bound Ig that was exclusively of 7Sgamma2 class. Furthermore, neither lymphoid tumor had a complement receptor. Thus both tumors oringinated from a particular B-cell population, which suggests that this B-cell type is associated with an SV40 receptor.

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