Dynein motility: four heads are better than two
- PMID: 16332531
- DOI: 10.1016/j.cub.2005.11.021
Dynein motility: four heads are better than two
Abstract
Cytoplasmic dynein is a microtubule-based motor protein that transports membranes in cells. The movement driven by a single dynein molecule in vitro is not as robust as dynein-driven movements in cells. A new study suggests that transport by multiple dyneins is more similar to cellular motions.
Similar articles
-
Transport of fungal RAB11 secretory vesicles involves myosin-5, dynein/dynactin/p25, and kinesin-1 and is independent of kinesin-3.Mol Biol Cell. 2017 Apr 1;28(7):947-961. doi: 10.1091/mbc.E16-08-0566. Epub 2017 Feb 16. Mol Biol Cell. 2017. PMID: 28209731 Free PMC article.
-
Building complexity: an in vitro study of cytoplasmic dynein with in vivo implications.Curr Biol. 2005 Dec 6;15(23):2075-85. doi: 10.1016/j.cub.2005.10.039. Curr Biol. 2005. PMID: 16332532
-
She1-mediated inhibition of dynein motility along astral microtubules promotes polarized spindle movements.Curr Biol. 2012 Dec 4;22(23):2221-30. doi: 10.1016/j.cub.2012.10.017. Epub 2012 Nov 8. Curr Biol. 2012. PMID: 23142046 Free PMC article.
-
Molecular motors: strategies to get along.Curr Biol. 2004 Nov 23;14(22):R971-82. doi: 10.1016/j.cub.2004.10.046. Curr Biol. 2004. PMID: 15556858 Review.
-
Motor-cargo interactions: the key to transport specificity.Trends Cell Biol. 2002 Jan;12(1):21-7. doi: 10.1016/s0962-8924(01)02184-5. Trends Cell Biol. 2002. PMID: 11854006 Review.
Cited by
-
Structural regulation and dynamic behaviour of organelles during plant meiosis.Front Cell Dev Biol. 2022 Oct 25;10:925789. doi: 10.3389/fcell.2022.925789. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36393860 Free PMC article. Review.
-
Multiple roles of the cytoskeleton in autophagy.Biol Rev Camb Philos Soc. 2009 Aug;84(3):431-48. doi: 10.1111/j.1469-185X.2009.00082.x. Biol Rev Camb Philos Soc. 2009. PMID: 19659885 Free PMC article. Review.
-
Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress.Naunyn Schmiedebergs Arch Pharmacol. 2008 Dec;378(6):599-608. doi: 10.1007/s00210-008-0330-7. Epub 2008 Jul 29. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18663430
-
PATHOLOGIES OF AXONAL TRANSPORT IN NEURODEGENERATIVE DISEASES.Transl Neurosci. 2012 Dec 1;3(4):355-372. doi: 10.2478/s13380-012-0044-7. Transl Neurosci. 2012. PMID: 23750323 Free PMC article.
-
Walking motion of an overdamped active particle in a ratchet potential.J Biol Phys. 2012 Mar;38(2):305-16. doi: 10.1007/s10867-011-9249-1. Epub 2011 Dec 2. J Biol Phys. 2012. PMID: 23449554 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources