Teaching resources. Regulation of complexes by cytoskeletal elements: integrins serve as force transducers linking mechanical stimuli and biochemical signals

Abstract

This Teaching Resource provides a summary and slides derived from a lecture on the integrin family members and the downstream signaling pathways they activate; it is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture focuses on the capacity of integrins to serve as mechanotransducers, with particular emphasis on signaling mechanisms downstream of integrins.