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Review
. 1992 Feb;2(1):61-3.
doi: 10.1016/s0959-437x(05)80323-5.

Genetic variation and quasi-species

E Domingo  1
Affiliations
Review

Genetic variation and quasi-species

E Domingo. Curr Opin Genet Dev. 1992 Feb.

Abstract

During the past year the relative fitness, that is, overall replication ability, and the fitness gain of animal virus variants have been quantified, providing new insight into the dynamics for the generation of RNA virus quasi-species. Measurements of mutant frequencies and rates of genetic diversification have confirmed the extreme complexity of RNA virus and retrovirus populations.

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