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. 2005 Dec;3(12):e421.
doi: 10.1371/journal.pbio.0030421. Epub 2005 Dec 13.

Selenoproteins--tracing the role of a trace element in protein function

Affiliations

Selenoproteins--tracing the role of a trace element in protein function

Thressa C Stadtman. PLoS Biol. 2005 Dec.

Abstract

Selenium is an important component of several enzymes, replacing sulfur in cysteine residues. Its discovery and significance are described in this primer.

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Figures

Figure 1
Figure 1. Schematic Illustrations Comparing the Enzymatic Reactions of Three Mammalian MsrBs
MsrB1 is a selenium-containing protein, whereas MsrB2 and MsrB3 contain cysteine in the active site. (Illustration: Rusty Howson, sososo design)

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