Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Dec;5(6):1069-78.
doi: 10.1586/14737140.5.6.1069.

Targeting the stromal fibroblasts: a novel approach to melanoma therapy

Keiran S M Smalley  1 , Mercedes Lioni, Meenhard Herlyn
Affiliations
Review

Targeting the stromal fibroblasts: a novel approach to melanoma therapy

Keiran S M Smalley et al. Expert Rev Anticancer Ther. 2005 Dec.

Abstract

Classically, cancer is thought of as a genetic disease, where the step-wise acquisition of mutations initiates and drives progression. More recent thinking posits that, although cancers are initiated through genetic mutation, progression is often the result of dynamic interactions between the tumor cells and their surrounding environment.

PubMed Disclaimer

Substances

LinkOut - more resources