doi: 10.1128/JVI.15.2.420-422.1975.
Malignant transformation of hamster kidney cells by BK virus
- PMID: 163364
- PMCID: PMC354469
- DOI: 10.1128/JVI.15.2.420-422.1975
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Malignant transformation of hamster kidney cells by BK virus
J Virol.
1975 Feb.
Abstract
Primary hamster kidney cells were transformed by BK virus, a new human papovavirus. Transformed (HKBK) cell produced BK virus T antigen and induced tumors in hamsters that developed antibodies to BK virus T antigen. BK virus was rescued from HKBK cells by Sendai virus-assisted fusion with permissive cells. One out of six cell lines derived from HKBK cell-induced tumors showed the same characteristics as HKBK cells.
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