Genital vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation

Abstract

Background: Genital vitiligo is common and has a deleterious effect on the psychosexual function of patients. It is well known that glabrous skin (non-hair-bearing skin such as below the ankles, genitalia, lips, distal ends of fingers) rarely responds to the therapy unless it has some residual pigment.

Objective: The objective was to report genital vitiligo treated successfully by autologous, noncultured, melanocyte-keratinocyte cell transplantation.

Methods: Three cases of clinically stable genital vitiligo were treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.

Results: All lesions treated repigmented almost completely. All patients were very satisfied with the excellent cosmetic results.

Conclusion: Autologous, noncultured melanocyte-keratinocyte cell transplantation may be an effective surgical treatment for management of genital vitiligo.