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. 2006 Jan 30;146(1):83-5.
doi: 10.1016/j.pscychresns.2005.09.004. Epub 2005 Dec 7.

MRI study of corpus callosum in children and adolescents with bipolar disorder

A Sibel Yasar  1 , E Serap Monkul, Roberto B Sassi, David Axelson, Paolo Brambilla, Mark A Nicoletti, John P Hatch, Matcheri Keshavan, Neal Ryan, Boris Birmaher, Jair C Soares
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MRI study of corpus callosum in children and adolescents with bipolar disorder

A Sibel Yasar et al. Psychiatry Res. .

Abstract

This structural magnetic resonance imaging study examined the length, areas, and circularity of the corpus callosum (CC) in 16 children and adolescents with bipolar disorder and 21 healthy controls. Bipolar disorder patients had lower circularity of the CC splenium compared with healthy controls. No significant differences in CC length or area were observed, suggesting that reported CC abnormalities appear late in the course of bipolar disorder.

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