Longitudinal analysis of Severe Acute Respiratory Syndrome (SARS) coronavirus-specific antibody in SARS patients
- PMID: 16339072
- PMCID: PMC1317065
- DOI: 10.1128/CDLI.12.12.1455-1457.2005
Longitudinal analysis of Severe Acute Respiratory Syndrome (SARS) coronavirus-specific antibody in SARS patients
Abstract
The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.
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References
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- Chen, Y. C., L. M. Huang, C. C. Chan, C. P. Su, S. C. Chang, Y. Y. Chang, M. L. Chen, C. C. Hung, W. J. Chen, F. Y. Lin, Y. T. Lee, and The SARS Research Group of National Taiwan University College of Medicine and National Taiwan University Hospital. 2004. SARS in hospital emergency room. Emerg. Infect. Dis. 10:782-788. - PMC - PubMed
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- Hseuh, P. R., C. H. Hsiao, S. H. Yeh, W. K. Wang, P. J. Chen, J. T. Wang, S. C. Chang, C. L. Kao, P. C. Yang, and The SARS Research Group of National Taiwan University College of Medicine and National Taiwan University Hospital. 2003. Microbiologic characteristics, serologic response, and clinical manifestations in severe acute respiratory syndrome, Taiwan. Emerg. Infect. Dis. 9:1163-1167. - PMC - PubMed
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