Successful pregnancies following fertility-preserving treatment for ovarian carcinoma

Abstract

Background: A 30-year-old woman underwent a routine sonogram at 6 weeks of gestation during her first pregnancy and was found to have a 6 cm complex right-ovarian mass, thought to be a dermoid cyst. The pregnancy progressed to term and the patient went on to have a normal vaginal delivery. At 3 months postpartum, she underwent a laparoscopic ovarian cystectomy. Preoperative serum cancer antigen 125 was within the normal range at 23.6 U/ml.

Investigations: Pelvic ultrasound, evaluation of serum cancer antigen 125, abdominal and pelvic CT scans.

Diagnosis: Stage IA clear-cell epithelial carcinoma of the right ovary.

Management: Laparoscopic ovarian cystectomy, dilation and curettage, laparotomy, right salpingo-oophorectomy, infracolic omentectomy, peritoneal biopsy, peritoneal washing, appendectomy, bilateral pelvic and para-aortic lymphadenectomy, adjuvant chemotherapy with paclitaxel and carboplatin.