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Clinical Trial
. 2006 Feb;103(2):136-40.
doi: 10.1007/s00347-005-1282-7.

[Seasonal fluctuations and influence of nutrition on macular pigment density]

[Article in German]
C Jahn  1 , C Brinkmann, A Mössner, H Wüstemeyer, U Schnurrbusch, S Wolf
Affiliations
Free article
Clinical Trial

[Seasonal fluctuations and influence of nutrition on macular pigment density]

[Article in German]
C Jahn et al. Ophthalmologe. 2006 Feb.
Free article

Abstract

Purpose: We have previously reported on measuring macular pigment density (MPD) with a scanning laser ophthalmoscope (HRA, Heidelberg Engineering, Heidelberg, Germany). This study war undertaken to evaluate the variation of MPD over a period of 1 year in healthy subjects.

Method: We used autofluorescence images recorded with a HRA to evaluate MPD with a 2 degrees circle centered on the fovea. Healthy subjects were included in the study and MPD measurements were repeated every 2 months over a period of 1 year.

Results: We included a total of 30 healthy subjects aged 19-34 years (mean: 23+/-2 years). Mean MPD at time point 1 was 0.215+/-0.056 density units (DU), at time point 2 0.235+/-0.051 DU, at time point 3 0.218+/-0.055 DU, at time point 4 0.228+/-0.057 DU, at time point 5 0.225+/-0.053 DU, and at time point 6 0.203+/-0.050 DU. The statistical analysis revealed no significant variation of MPD over the follow-up period of 1 year.

Conclusion: This study demonstrates that MPD shows no variation over a period of 1 year in healthy subjects.

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