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Comparative Study
. 2005 Dec 13;65(11):1817-9.
doi: 10.1212/01.wnl.0000187068.92184.63.

Comparison of family histories in FTLD subtypes and related tauopathies

J S Goldman  1 , J M Farmer, E M Wood, J K Johnson, A Boxer, J Neuhaus, C Lomen-Hoerth, K C Wilhelmsen, V M-Y Lee, M Grossman, B L Miller
Affiliations
Comparative Study

Comparison of family histories in FTLD subtypes and related tauopathies

J S Goldman et al. Neurology. .

Abstract

Pedigrees from 269 patients with frontotemporal lobar degeneration (FTLD), including frontotemporal dementia (FTD), FTD with ALS (FTD/ALS), progressive nonfluent aphasia, semantic dementia (SD), corticobasal degeneration, and progressive supranuclear palsy were analyzed to determine the degree of heritability of these disorders. FTD/ALS was the most and SD the least heritable subtype. FTLD syndromes appear to have different etiologies and recurrence risks.

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