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. 1990 Apr;56(4):1162-3.
doi: 10.1128/aem.56.4.1162-1163.1990.

Identification of deep-sea-sediment bacteria which produce tetrodotoxin

H K Do  1 , K Kogure, U Simidu
Affiliations

Identification of deep-sea-sediment bacteria which produce tetrodotoxin

H K Do et al. Appl Environ Microbiol. 1990 Apr.

Abstract

Forty-nine bacterial strains were isolated from deep-sea sediments. Among them, 22 strains were shown by the tissue culture assay method to produce sodium channel blockers. For some strains, high-performance liquid chromatography analysis confirmed that the blocker was tetrodotoxin. Tetrodotoxin-producing bacteria seem to be widespread in marine sediment.

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References

    1. Appl Environ Microbiol. 1987 Jul;53(7):1714-5 - PubMed
    1. Toxicon. 1988;26(2):191-7 - PubMed
    1. J Biochem. 1986 Jan;99(1):311-4 - PubMed

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