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Review
. 2005;2(6):537-40, 511-2.
doi: 10.1513/pats.200507-067DS.

Bioluminescence imaging

Ruxana T Sadikot  1 , Timothy S Blackwell
Affiliations
Review

Bioluminescence imaging

Ruxana T Sadikot et al. Proc Am Thorac Soc. 2005.

Abstract

Bioluminescence refers to the process of visible light emission in living organisms. Bioluminescence imaging is a powerful methodology that has been developed over the last decade as a tool for molecular imaging of small laboratory animals, enabling the study of ongoing biological processes in vivo. This form of optical imaging is low cost and noninvasive and facilitates real-time analysis of disease processes at the molecular level in living organisms. In this article, we provide a brief introduction to bioluminescence imaging technology and discuss its applications in mouse models of lung inflammation/injury, bacterial pneumonia, and tumor growth and metastasis.

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References

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