doi: 10.1039/b513165k.
Epub 2005 Nov 23.
Advances in glycoprotein synthesis
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- PMID: 16353085
- DOI: 10.1039/b513165k
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Advances in glycoprotein synthesis
Chem Commun (Camb).
.
Abstract
The development of chemical and enzymatic methods for the synthesis of homogeneous glycoproteins is a fascinating challenge at the interface between chemistry and biology. Discussed here are the currently available methods for preparation of homogeneous glycoproteins. These methods include (1) glycopeptide ligation; (2) glycoprotein remodeling; and (3) in vivo suppressor tRNA technology.
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