Editorial
doi: 10.1093/humupd/dmi051.
Man-made versus female-made environment--will the real capacitation please stand up?
- PMID: 16354709
- DOI: 10.1093/humupd/dmi051
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Editorial
Man-made versus female-made environment--will the real capacitation please stand up?
Hum Reprod Update.
2006 Jan-Feb.
Abstract
Two recent reviews discuss the importance of the female tract in regulating the function of the spermatozoon during its eventful journey to the site of fertilization in this journal. However, our understanding of the nature of this journey, specifically in the human, is remarkably poor. What is also clear is the discourse between what is likely happening in vivo and the design of our experiments in vitro. Our conclusion is that, to date, we have been studying the spermatozoa in the wrong environment, in the wrong way and at the wrong time.
Comment on
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Biological basis for human capacitation.Hum Reprod Update. 2005 May-Jun;11(3):205-14. doi: 10.1093/humupd/dmi010. Epub 2005 Apr 7. Hum Reprod Update. 2005. PMID: 15817522 Review.
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Sperm transport in the female reproductive tract.Hum Reprod Update. 2006 Jan-Feb;12(1):23-37. doi: 10.1093/humupd/dmi047. Epub 2005 Nov 4. Hum Reprod Update. 2006. PMID: 16272225 Review.
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